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CCDC28A deficiency causes head-tail coupling defects and immotility in murine spermatozoa

5 Nov 2024

Abstract excerpt

Male infertility presents a substantial challenge in reproductive medicine, often attributed to impaired sperm motility. The present study investigates the role of CCDC28A, a protein expressed specifically in male germ cells, whose paralog CCDC28B has been implicated in ciliogenesis. We identify unique expression patterns for CCDC28A and CCDC28B within the mouse testes, where CCDC28A is expressed in germ cells,...

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PMID: 39500989
DOI: 10.1038/s41598-024-78453-9

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CCDC28A deficiency causes head-tail coupling defects and immotility in murine spermatozoaPMID 39500989Read ↗

CCDC28A deficiency causes sperm head defects, reduced sperm motility and male infertility in miceSemantic proximity Read ↗

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