Article
The genetic architecture of morphological abnormalities of the sperm tail.
Human genetics - 1 Jan 2021
Touré Aminata, Martinez Guillaume, Kherraf Zine-Eddine, Cazin Caroline, Beurois Julie, Arnoult Christophe, Ray Pierre F, Coutton Charles
Abstract excerpt
Spermatozoa contain highly specialized structural features reflecting unique functions required for fertilization. Among them, the flagellum is a sperm-specific organelle required to generate the motility, which is essential to reach the egg. The flagellum integrity is, therefore, critical for normal sperm function and flagellum defects consistently lead to male infertility due to reduced or absent sperm motility...
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