Article

CCDC113 stabilizes sperm axoneme and head-tail coupling apparatus to ensure male fertility

2024-12-13

Abstract excerpt

The structural integrity of the sperm is crucial for male fertility, defects in sperm head-tail linkage and flagellar axoneme are associated with acephalic spermatozoa syndrome (ASS) and the multiple morphological abnormalities of the sperm flagella (MMAF). Notably, impaired head-tail coupling apparatus (HTCA) often accompanies defects in the flagellum structure, however, the molecular mechanisms underlying this p...

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Literature Corpus work: 4843647d-1763-534d-bd05-24e2374404ee
DOI: 10.7554/elife.98016.3

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