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Transcriptomic and functional analysis of Aβ <sub>1-42</sub> oligomer-stimulated human monocyte-derived microglia-like cells

2021-08-13

Abstract excerpt

Dysregulation of microglial function contributes to Alzheimer’s disease (AD) pathogenesis. Several genetic and transcriptome studies have revealed microglia specific genetic risk factors, and changes in microglia expression profiles in AD pathogenesis, viz . the human-Alzheimer’s microglia/myeloid (HAM) profile in AD patients and the disease-associated microglia profile (DAM) in AD mouse models. The transcription...

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Literature Corpus work
48603173-33e9-5169-acc9-c022915e2bbd
DOI
10.1101/2021.08.12.456055
Open publication

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Transcriptomic and functional analysis of Aβ <sub>1-42</sub> oligomer-stimulated human monocyte-derived microglia-like cellsDOI 10.1101/2021.08.12.456055
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