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Integrating spatial omics with routine haematoxylin and eosin in formalin-fixed paraffin-embedded: a step-by-step clinical workflow

2025-10-09

Abstract excerpt

Haematoxylin and eosin (H&E) remain the foundation of tissue diagnosis, yet many clinical questions, tumour–immune architecture, spatial heterogeneity, and predictors of therapy response, require molecular context that routine slides cannot provide. Spatial omics closes this gap by mapping RNA and proteins in situ while preserving morphology, and recent platforms are increasingly compatible with formalin-fixed par...

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Literature Corpus work
a073a22d-a35b-5555-8a52-222aa519bae7
DOI
10.12688/f1000research.170680.1
Open publication

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Integrating spatial omics with routine haematoxylin and eosin in formalin-fixed paraffin-embedded: a step-by-step clinical workflowDOI 10.12688/f1000research.170680.1
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