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Article

Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function.

The Journal of allergy and clinical immunology - 1 Mar 2016

Mitson-Salazar Alyssa, Yin Yuzhi, Wansley Daniel L, Young Michael, Bolan Hyejeong, Arceo Sarah, Ho Nancy, Koh Christopher, Milner Joshua D, Stone Kelly D, Wank Stephen A, Prussin Calman

Abstract excerpt

BACKGROUND: IL-5(+) pathogenic effector T(H)2 (peT(H)2) cells are a T(H)2 cell subpopulation with enhanced proinflammatory function that has largely been characterized in murine models of allergic inflammation. OBJECTIVE: We sought to identify phenotype markers for human peT(H)2 cells and characterize their function in patients with allergic eosinophilic inflammatory diseases. METHODS: Patients with eosinophilic...

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PMID: 26431580
DOI: 10.1016/j.jaci.2015.08.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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