Rhinovirus Infection Drives Complex Host Airway Molecular Responses in Children With Cystic Fibrosis

Abstract excerpt

Early life viral infections are responsible for pulmonary exacerbations that can contribute to disease progression in young children with CF. The most common respiratory viruses detected in the CF airway are human rhinoviruses (RV) and augmented airway inflammation in CF has been attributed to dysregulated airway epithelial responses, although evidence has been conflicting. Here, we exposed airway epithelial...

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