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Variation in the response to antibiotics and life-history across the major Pseudomonas aeruginosa clone type (mPact) panel.

Microbiology spectrum - 2 Jul 2024

Tueffers Leif, Batra Aditi, Zimmermann Johannes, Botelho João, Buchholz Florian, Liao Junqi, Mendoza Mejía Nicolás, Munder Antje, Klockgether Jens, Tüemmler Burkhard, Rupp Jan, Schulenburg Hinrich

Abstract excerpt

Pseudomonas aeruginosa is a ubiquitous, opportunistic human pathogen. Since it often expresses multidrug resistance, new treatment options are urgently required. Such new treatments are usually assessed with one of the canonical laboratory strains, PAO1 or PA14. However, these two strains are unlikely representative of the strains infecting patients, because they have adapted to laboratory conditions and do not...

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Identifiers

PMID: 38860784
DOI: 10.1128/spectrum.00143-24
PMCID: PMC11218531

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