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B-cell specific expression of the murine <i> Myd88 <sup>L252P</sup> </i> mutation correlates with the establishment of an immunosuppressive microenvironnement in Waldenström macroglobulinemia lymphoplasmacytic lymphoma

2023-09-29

Abstract excerpt

Waldenström macroglobulinemia is a rare and indolent lymphoproliferative disorder genetically characterized by the presence of the L265P mutation in the MYD88 gene in nearly each case. Despite its slow progression, Waldenström macroglobulinemia remain incurable due to the lack of specific treatments. The importance of the tumour microenvironment was well documented since the last decade especially concerning the...

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Literature Corpus work
c0b2b040-ef44-5f2c-a489-a5090733423e
DOI
10.1101/2023.09.28.559899
Open publication

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B-cell specific expression of the murine <i> Myd88 <sup>L252P</sup> </i> mutation correlates with the establishment of an immunosuppressive microenvironnement in Waldenström macroglobulinemia lymphoplasmacytic lymphomaDOI 10.1101/2023.09.28.559899
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