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Article

Role of plasma cells in Waldenström macroglobulinaemia.

Pathology - 1 Jun 2017

El-Ayoubi Ali, Wang James Q, Hein Nadine, Talaulikar Dipti

Abstract excerpt

Waldenström macroglobulinaemia (WM) is an indolent mature B cell lymphoma characterised by an infiltrate of heterogeneous B cells and hypersecretion of IgM. There are two distinct cellular populations that can be distinguished on morphology and immunophenotyping within the bone marrow. The predominant lymphoplasmacytic compartment arises at an earlier stage in ontogeny, and is responsible for the cytopenias noted...

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PMID: 28483372
DOI: 10.1016/j.pathol.2017.02.004

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