Article
Novel approaches to targeting MYD88 in Waldenström macroglobulinemia.
Expert review of hematology - 1 Aug 2017
Castillo Jorge J, Hunter Zachary R, Yang Guang, Treon Steven P
Abstract excerpt
INTRODUCTION: Waldenström macroglobulinemia (WM) is an incurable lymphoma characterized by the accumulation of IgM-producing lymphoplasmacytic cells in the bone marrow and other organs. Although WM patients can experience prolonged remissions, the disease invariably recurs advocating for the need of novel treatments in order to achieve higher response and survival rates. The discovery of a recurrent mutation in...
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