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Article

Significances of MYD88L265P and CXCR4WHIM Mutations in Waldenstrom Macroglobulinemia.

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 20 Aug 2017

Meng Qi, Cao Xin-Xin, Li Jian

Abstract excerpt

Waldenstrom macroglobulinemia(WM) is a lymphoplasmacytic lymphoma characterized by serum monoclonal IgM immunoglobulin.Recently,the high mutation rates of MYD88L265P and CXCR4WHIM have been documented in WM.Furthermore,MYD88L265P and CXCR4WHIM are related to the response to target drugs.This article reviews the significances of MYD88L265P and CXCR4WHIM in the diagnosis and treatment of WM....

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Identifiers

PMID: 28877839
DOI: 10.3881/j.issn.1000-503X.2017.04.019

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