Article
BreakCA, a method to discover indels using ChIP-seq and ATAC-seq reads, finds recurrent indels in regulatory regions of neuroblastoma genomes
2019-04-11
Abstract excerpt
Most known cancer driver mutations are within protein coding regions of the genome, however, there are several important examples of oncogenic non-coding regulatory mutations. We developed a method to identify insertions and deletions (indels) in regulatory regions using aligned reads from chromatin immunoprecipitation followed by sequencing (ChIP-seq) or the assay for transposase-accessible chromatin (ATAC-seq)....
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Identifiers and source
- Literature Corpus work
- c09bc4d4-be0a-59a2-9f27-5a946065c4eb
- DOI
- 10.1101/605642