Article

ZFHX3 acts as a tumor suppressor in prostate cancer by targeting FTO-mediated m6A demethylation

2023-02-14

Abstract excerpt

<title>Abstract</title> <p>Zinc-finger homeobox 3 (ZFHX3, also known as ATBF1) suppresses prostatic tumorigenesis; ZFHX3 is frequently found to have numerous deletions when found in human prostate cancer (PCa). However, the underlying molecular function of ZFHX3 during prostatic tumorigenesis is not well understood. N6-methyladenosine (m6A) modification in RNA plays a critical role in the development of cancers;...

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Literature Corpus work: c06fd1c1-fbb8-52cb-935f-0ec1dcc5ec89
DOI: 10.21203/rs.3.rs-2467261/v1

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