Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HENMT1: an RNA methyltransferase in biology and disease.

Journal of Zhejiang University. Science. B - 4 May 2026

Jiang Shanghong, Zhao Yongchao, Cui Danrui

Abstract excerpt

HEN methyltransferase 1 (HENMT1) is an RNA methyltransferase that catalyzes 2'-O-methylation of P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) within the small RNA silencing pathway and methylates microRNAs (miRNAs). By stabilizing these RNA molecules, HENMT1 plays a pivotal role in regulating the biological processes that they target, thereby maintaining cellular homeostasis. Mutations in HENMT1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Infertility
Share to Methyltransferases
Share to MicroRNAs

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 42343633
DOI: 10.1631/jzus.B2500059
PMCID: PMC13294282

Genes

HENMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HENMT1: an RNA methyltransferase in biology and disease.PMID 42343633Read ↗

Exploring the role of m6A modification in cancerSemantic proximity Read ↗

The epigenetic landscape of renal cancer.Semantic proximity Read ↗

Main N6-Methyladenosine Readers: YTH Family Proteins in CancersSemantic proximity Read ↗

Epigenetic changes in cancer.Semantic proximity Read ↗

Connections between epigenetic gene silencing and human disease.Semantic proximity Read ↗

Epigenetic Factors and ncRNAs in Testicular CancerSemantic proximity Read ↗

DNA methylation and DNA methyltransferases.Semantic proximity Read ↗

Critical Roles of PIWIL1 in Human Tumors: Expression, Functions, Mechanisms, and Potential Clinical ImplicationsSemantic proximity Read ↗

Bioinformatic analysis of methyltransferase-like protein family reveals clinical and functional outcomes in human cancerSemantic proximity Read ↗

Internal m7G methylation: A novel epitranscriptomic contributor in brain development and diseasesSemantic proximity Read ↗

m6A RNA methylation: a pivotal regulator of tumor immunity and a promising target for cancer immunotherapySemantic proximity Read ↗

Pan-Cancer Analysis of Molecular Characteristics and Oncogenic Role of PRMT5 in Human CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.