Article

Nuclear transport under stress phenocopies transport defects in models of C9Orf72 ALS

2022-04-13

Abstract excerpt

The nucleus is the hallmark of eukaryotic life and transport to and from the nucleus occurs through the nuclear pore complex (NPC). There is a multitude of data connecting the nuclear transport machinery – i.e. the NPCs and associated nuclear transport factors - to neurodegenerative diseases, but the mechanisms are not well understood. Using Saccharomyces cerevisiae , we systematically studied how the expression...

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Identifiers and source

Literature Corpus work: c024e63a-e937-5df1-ac5a-1d27db0eed6d
DOI: 10.1101/2022.04.13.488135

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