When intracellular logistics fails--genetic defects in membrane trafficking.

Abstract excerpt

The number of human genetic disorders shown to be due to defects in membrane trafficking has greatly increased during the past five years. Defects have been identified in components involved in sorting of cargo into transport carriers, vesicle budding and scission, movement of vesicles along cytoskeletal tracks, as well as in vesicle tethering, docking and fusion at the target membrane. The nervous system is...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biological Transport
• Share to Hermanski-Pudlak Syndrome
• Share to Membrane Proteins