Article
Interorganelle competition for linoleic acid underlies steatotic liver pathology
2026-01-11
Abstract excerpt
Lipid droplets (LDs) are traditionally viewed as protective organelles that sequester potentially cytotoxic lipids. However, whether and how LD biogenesis in pathological contexts actively rewires interorganelle lipid homeostasis to drive organelle dysfunction and disease progression remains unexplored. Here, we identify the adipocyte-enriched protein calsyntenin 3β (CLSTN3B) as a critical promoter of metabolic dy...
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Identifiers and source
- Literature Corpus work
- bfccd480-06e5-5382-ae26-d337f8bb7405
- DOI
- 10.64898/2026.01.11.698890