Article

Fluid extraction from the left-right organizer uncovers mechanical properties needed for symmetry breaking

2022-04-22

Abstract excerpt

Humans and other vertebrates define body axis left-right asymmetry in the early stages of embryo development (Shiratori and Hamada, 2006). The mechanism behind left-right establishment is not fully understood (Mizuno et al ., 2020; Maerker et al ., 2021; Minegishi et al ., 2021). Symmetry breaking occurs in a dedicated organ called the left-right organizer (LRO) and involves motile cilia generating fluid-flow t...

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Literature Corpus work: bfa344d3-19e1-5e10-adce-c8818ebd96ee
DOI: 10.1101/2022.04.21.489023

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