Article

Novel Pan-ALDH Inhibitor KS100 Effectively Targets ALDH+/CD138⁻ Stem-like Cells to Overcome Relapse in Multiple Myeloma

2025-03-11

Abstract excerpt

Multiple myeloma (MM), a clonal plasma cell disorder is the second most frequent hematological malignancy in the United States. This malignancy is characterized by a series of symptoms such as bone lesions, hypercalcemia, renal failure, and anemia. The current clinical drugs in the market are successful in treating multiple myeloma patients into remission but does not address relapse where a more aggressive phenot...

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Literature Corpus work: bf7ddcaf-aea1-541d-a74d-8bad4a31d0c4
DOI: 10.1101/2025.03.06.641909

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