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Article

Multiple myeloma.

Lancet (London, England) - 25 Jul 2009

Raab Marc S, Podar Klaus, Breitkreutz Iris, Richardson Paul G, Anderson Kenneth C

Abstract excerpt

Multiple myeloma is characterised by clonal proliferation of malignant plasma cells, and mounting evidence indicates that the bone marrow microenvironment of tumour cells has a pivotal role in myeloma pathogenesis. This knowledge has already expanded treatment options for patients with multiple myeloma. Prototypic drugs thalidomide, bortezomib, and lenalidomide have each been approved for the treatment of this...

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PMID: 19541364
DOI: 10.1016/S0140-6736(09)60221-X

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