Article
Multiple Myeloma: Challenges Encountered and Future Options for Better Treatment.
International journal of molecular sciences - 31 Jan 2022
Das Srijit, Juliana Norsham, Yazit Noor Anisah Abu, Azmani Sahar, Abu Izuddin Fahmy
Abstract excerpt
Multiple myeloma (MM) is a malignant hematological disease. The disease is characterized by the clonal proliferation of malignant plasma cells in the bone marrow. MM accounts for 1.3% of all malignancies and has been increasing in incidence all over the world. Various genetic abnormalities, mutations, and translocation, including epigenetic modifications, are known to contribute to the disease's pathophysiology....
Topics
- Biological Products
- Combined Modality Therapy
- Drug Resistance, Neoplasm
- Epigenesis, Genetic
- Humans
- Multiple Myeloma
- Mutation
- Prognosis
- Translocation, Genetic
- Tumor Microenvironment