Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autophagy and Apoptosis: Current Challenges of Treatment and Drug Resistance in Multiple Myeloma

30 Dec 2022

Abstract excerpt

Over the past two decades, the natural history of multiple myeloma (MM) has evolved dramatically, owing primarily to novel agents targeting MM in the bone marrow microenvironment (BMM) pathways. However, the mechanisms of resistance acquisition remain a mystery and are poorly understood. Autophagy and apoptosis are tightly controlled processes and play a critical role in the cell growth, development, and survival...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Multiple Myeloma Research and Treatments
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36614089
DOI: 10.3390/ijms24010644

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autophagy and Apoptosis: Current Challenges of Treatment and Drug Resistance in Multiple MyelomaPMID 36614089Read ↗

Autophagy-related mechanisms for treatment of multiple myelomaSemantic proximity Read ↗

Molecular mechanisms in multiple myeloma drug resistance.Semantic proximity Read ↗

Different Strategies to Overcome Resistance to Proteasome Inhibitors—A Summary 20 Years after Their IntroductionSemantic proximity Read ↗

Molecular and immunological mechanisms of clonal evolution in multiple myelomaSemantic proximity Read ↗

Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?Semantic proximity Read ↗

Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanismsSemantic proximity Read ↗

Multiple myeloma.Semantic proximity Read ↗

A new autophagy-related nomogram and mechanism in multiple myelomaSemantic proximity Read ↗

Treatment Strategies Considering Micro-Environment and Clonal Evolution in Multiple MyelomaSemantic proximity Read ↗

Molecular pathogenesis of multiple myeloma and its premalignant precursorSemantic proximity Read ↗

Endoplasmic reticulum stress in the development of multiple myeloma and drug resistanceSemantic proximity Read ↗

Targeting mTOR signaling pathways in multiple myeloma: biology and implication for therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.