Article

Global profiling of human blood ILC subtypes reveals that NK cells produce homeostatic cytokine amphiregulin and sheds light on HIV-1 pathogenesis

2021-04-20

Abstract excerpt

The interrelatedness of human blood innate lymphoid cell (ILC) subsets, and how they are perturbed by HIV-1, remains unclear. Transcriptional and chromatin profiling separated blood ILCs into ILC2s, ILCPs, one cluster that included CD56 dim and CD56 − NK cells, and CD56 hi NK cells that have features of both CD56 dim/– NK cells and ILCs. In contrast to mice, human NK cells expressed tissue repair protein amphi...

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Literature Corpus work: bf37094c-e3ed-5743-8ae8-5ce179119b57
DOI: 10.1101/2021.04.20.440368

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