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Time-resolved X-ray solution scattering unveils the sequence of events leading to human Hb heme capture by <i>Staphylococcus aureus</i> IsdB

2023-08-04

Abstract excerpt

Infections caused by Staphylococcus aureus depend on its ability to acquire nutrients. One essential nutrient is iron, which is obtained from the heme of the human host hemoglobin (Hb) through a protein machinery called Iron-regulated Surface Determinant (Isd). IsdB is the protein in charge of heme extraction from Hb, which is the first step of the chain of events leading to iron transfer to the bacterium cell in...

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Literature Corpus work
bf21a166-1d5d-5a01-b628-3b47504b0d7a
DOI
10.1101/2023.08.04.551941
Open publication

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Time-resolved X-ray solution scattering unveils the sequence of events leading to human Hb heme capture by <i>Staphylococcus aureus</i> IsdBDOI 10.1101/2023.08.04.551941
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