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Article

Structural and functional characterization of the <i>Staphylococcus aureus</i> virulence factor and vaccine candidate FhuD2

1 Nov 2012

Abstract excerpt

Staphylococcus aureus is a human pathogen causing globally significant morbidity and mortality. The development of antibiotic resistance in S. aureus highlights the need for a preventive vaccine. In the present paper we explore the structure and function of FhuD2 (ferric-hydroxamate uptake D2), a staphylococcal surface lipoprotein mediating iron uptake during invasive infection, recently described as a promising...

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PMID: 23113737
DOI: 10.1042/bj20121426

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