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Heme Coordination by Staphylococcus aureus IsdE

1 Aug 2007

Abstract excerpt

Staphylococcus aureus is a Gram-positive bacterial pathogen and a leading cause of hospital acquired infections. Because the free iron concentration in the human body is too low to support growth, S. aureus must acquire iron from host sources. Heme iron is the most prevalent iron reservoir in the human body and a predominant source of iron for S. aureus. The iron-regulated surface determinant (Isd) system removes...

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PMID: 17666394
DOI: 10.1074/jbc.m704602200

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