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Gene networks reveal stem-cell state convergence during preneoplasia and progression to malignancy in multistage skin carcinogenesis

2023-05-10

Abstract excerpt

Adult mammalian stem cells play critical roles in normal tissue homeostasis, as well as in tumor development, by contributing to cell heterogeneity, plasticity, and development of drug resistance. The relationship between different types of normal and cancer stem cells is highly controversial and poorly understood. Here, we carried out gene expression network analysis of normal and tumor samples from genetically h...

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Literature Corpus work
bf0ef552-4813-57df-88fc-21dd920a9e36
DOI
10.1101/2023.05.08.539863
Open publication

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Gene networks reveal stem-cell state convergence during preneoplasia and progression to malignancy in multistage skin carcinogenesisDOI 10.1101/2023.05.08.539863
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