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Direct single cell-type gene expression analysis in Whole blood: Novel ratio-based gene expression biomarkers using 2 novel monocyte reference genes ( <i>PSAP</i> and <i>CTSS</i> ) for monitoring bacterial infection

2025-01-28

Abstract excerpt

<h4>Background</h4> To determine single cell-type specific gene expression in peripheral blood (PB) requires either prior labour-intense cell sorting or expensive single-cell RNA sequencing. We developed and validated a novel ratio-based biomarker (RBB) called Direct Leukocyte Subpopulation-Transcript Abundance (DIRECT LS-TA) assay that allows quantification of monocyte-specific gene expression directly from peri...

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Literature Corpus work
bacae1db-8f17-5d7d-b897-30e400102b81
DOI
10.1101/2025.01.27.634977
Open publication

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Direct single cell-type gene expression analysis in Whole blood: Novel ratio-based gene expression biomarkers using 2 novel monocyte reference genes ( <i>PSAP</i> and <i>CTSS</i> ) for monitoring bacterial infectionDOI 10.1101/2025.01.27.634977
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