Article

Derivation, validation, and transcriptomic assessment of pediatric septic shock phenotypes identified through latent profile analyses: Results from a prospective multi-center observational cohort

2023-12-06

Abstract excerpt

<title>Abstract</title> <p>Background Sepsis poses a grave threat, especially among children, but treatments are limited due to clinical and biological heterogeneity among patients. Thus, there is an urgent need for precise subclassification of patients to guide therapeutic interventions. Methods We used clinical, laboratory, and biomarker data from a prospective multi-center pediatric septic shock cohort to de...

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Literature Corpus work: bef505b4-be5c-52ae-8d88-0027475329e5
DOI: 10.21203/rs.3.rs-3692289/v1

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