Article

A novel approach to identifying marker genes and estimating the cellular composition of whole blood from gene expression profiles

2016-02-03

Abstract excerpt

Measuring genome-wide changes in transcript abundance in circulating peripheral whole blood cells is a useful way to study disease pathobiology and may help elucidate biomarkers and molecular mechanisms of disease. The sensitivity and interpretability of analyses carried out in this complex tissue, however, are significantly affected by its dynamic heterogeneity. It is therefore desirable to quantify this heteroge...

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Literature Corpus work: be8ee1ff-9eb1-5385-be1a-3e531990c86a
DOI: 10.1101/038794

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