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Article

Investigation of variation in gene expression profiling of human blood by extended principle component analysis.

PloS one - 1 Jan 2011

Xu Qinghua, Ni Shujuan, Wu Fei, Liu Fang, Ye Xun, Mougin Bruno, Meng Xia, Du Xiang

Abstract excerpt

BACKGROUND: Human peripheral blood is a promising material for biomedical research. However, various kinds of biological and technological factors result in a large degree of variation in blood gene expression profiles. METHODOLOGY/PRINCIPAL FINDINGS: Human peripheral blood samples were drawn from healthy volunteers and analysed using the Human Genome U133Plus2 Microarray. We applied a novel approach using the...

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PMID: 22046403
DOI: 10.1371/journal.pone.0026905
PMCID: PMC3203156

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