Article

Single Cell Transcriptomics and Surface Protein Expression Reveal Distinct Cellular and Molecular Phenotypes in Human RPESC-RPE and PSC-RPE

2026-03-01

Abstract excerpt

<h4>ABSTRACT</h4> Current retinal pigment epithelium (RPE) cell replacement strategies in trials for age-related macular degeneration (AMD) are based on either pluripotent stem cell (PSC) or adult RPE stem cell (RPESC) sources. We used Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-Seq) to simultaneously assess single-cell transcriptomic and surface protein information, comparing these two R...

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Literature Corpus work: be7b7995-68be-55ee-b618-2b304cbc267e
DOI: 10.64898/2026.02.26.708319

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