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Transcriptome analysis and molecular signature of human retinal pigment epithelium

1 Apr 2010

Abstract excerpt

Retinal pigment epithelium (RPE) is a polarized cell layer critical for photoreceptor function and survival. The unique physiology and relationship to the photoreceptors make the RPE a critical determinant of human vision. Therefore, we performed a global expression profiling of native and cultured human fetal and adult RPE and determined a set of highly expressed 'signature' genes by comparing the observed RPE...

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PMID: 20360305
DOI: 10.1093/hmg/ddq129

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