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Identifying biomarkers of heterogeneity and transplantation efficacy in retinal pigment epithelial cells

19 Aug 2023

Abstract excerpt

Transplantation of retinal pigment epithelial (RPE) cells holds great promise for patients with retinal degenerative diseases, such as age-related macular degeneration. In-depth characterization of RPE cell product identity and critical quality attributes are needed to enhance efficacy and safety of replacement therapy strategies. Here, we characterized an adult RPE stem cell-derived (RPESC-RPE) cell product...

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PMID: 37728563
DOI: 10.1084/jem.20230913

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