Article

Molecular profiling of retinal pigment epithelial cell differentiation for therapeutic use

2021-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) are a promising cell source to treat age-related macular degeneration (AMD). Despite several ongoing clinical studies, detailed single cell mapping of the transient cellular and molecular dynamics from the pluripotent state to mature RPE has not been performed. Here we conduct single-cell transcriptomic analyses of 25,...

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Literature Corpus work: 5b87b8f2-6f6e-535f-8a23-f5f98ac7ae35
DOI: 10.1101/2021.01.31.429014

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