Article

Single-cell transcriptomic atlas of human retina from Chinese donors reveals population-specific cellular diversity

2025-03-17

Abstract excerpt

The human retina exhibits complex cellular heterogeneity which is critical for visual function, yet comprehensive ethnic-specific references are scarce in ophthalmic transcriptomics. The lack of single-cell RNA sequencing (scRNA-seq) data from Asian populations particularly Chinese donors imposes significant limitations in understanding population-specific retinal biology. We constructed the first comprehensive si...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2c326811-7168-5a02-84ed-15f79d46d33b
DOI: 10.1101/2025.03.16.643491

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell transcriptomic atlas of human retina from Chinese donors reveals population-specific cellular diversityDOI 10.1101/2025.03.16.643491Read

Generation of human neural retina transcriptome atlas by single cell RNA sequencingSemantic proximity Read

Integrated multi-omics single cell atlas of the human retinaSemantic proximity Read

Integrated multi-omics single cell atlas of the human retinaSemantic proximity Read

Cell Atlas of the Human Fovea and Peripheral RetinaSemantic proximity Read

Integrative single-cell and bulk RNA-seq analysis in human retina identified cell type-specific composition and gene expression changes for age-related macular degenerationSemantic proximity Read

Cell Atlas of The Human Fovea and Peripheral RetinaSemantic proximity Read

Interpretable Aging Signatures in Human Retinal Cell Types Revealed by Single-Cell RNA Sequencing and Sparse Logistic RegressionSemantic proximity Read

Iso-Seq enables discovery of novel isoform variants in human retina at single cell resolutionSemantic proximity Read

Implication of specific retinal cell-type involvement and gene expression changes in AMD progression using integrative analysis of single-cell and bulk RNA-seq profilingSemantic proximity Read

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration.Semantic proximity Read

Transcriptomic Analysis of the Ocular Posterior Segment Completes a Cell Atlas of the Human EyeSemantic proximity Read

A single-cell transcriptome atlas of the aging human and macaque retinaSemantic proximity Read