Article
Association of heparan sulfate proteoglycans SDC1 and SDC4 polymorphisms with breast cancer in an Australian Caucasian population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Mar 2015
Okolicsanyi Rachel K, Buffiere Anne, Jacinto Jose M E, Chacon-Cortes Diego, Chambers Suzanne K, Youl Philippa H, Haupt Larisa M, Griffiths Lyn R
Abstract excerpt
Breast cancer is a common disease in both developing and developed countries with early identification and treatment improving prognosis and survival. Heparan sulfate proteoglycans (HSPGs) are key components of the extracellular matrix (ECM) that mediate cell adhesion, motility, proliferation, invasion and cell signalling. Members of the syndecan family of HSPGs have been identified to be involved in breast...
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