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Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

2019-04-13

Abstract excerpt

<h4>ABSTRACT</h4> DNA, when folded into nanostructures of customizable shapes, is capable of spacing and arranging external ligands in a desired geometric pattern with nanometer-precision. This allows DNA to serve as an excellent, biocompatible scaffold for complex spatial pattern-recognizing displays. In this report, we demonstrate that a templated designer DNA nanostructure achieves multi-ligand display with pr...

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Literature Corpus work
be6a75b0-125a-5b66-8fb4-4828fc95923d
DOI
10.1101/608380
Open publication

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