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Integrated Micropillar Polydimethylsiloxane Accurate CRISPR Detection (IMPACT) System for Rapid Viral DNA Sensing

2020-03-20

Abstract excerpt

<h4>ABSTRACT</h4> A fully Integrated Micropillar Polydimethylsiloxane Accurate CRISPR Detection (IMPACT) system is developed for viral DNA detection. This powerful system is patterned with high-aspect ratio micropillars to enhance reporter probe binding. After surface modification and probe immobilization, CRISPR Cas12a/crRNA complex is injected into the fully enclosed system. With the presence of double-stranded...

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Literature Corpus work: 7383565b-f157-5f5c-8cd0-0091ceb44a71
DOI: 10.1101/2020.03.17.994137

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