Article
Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy
2019-05-14
Abstract excerpt
Homeostatic maintenance of corneal endothelial cells is essential for maintenance of corneal deturgescence and corneal transparency. In Fuchs endothelial corneal dystrophy (FECD), an accelerated loss and dysfunction of endothelial cells leads to progressively severe visual impairment. An abnormal accumulation of extracellular matrix is a distinctive hallmark of the disease, however the molecular pathogenic mechani...
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Identifiers and source
- Literature Corpus work
- be1ac946-a375-543b-8f83-812379f35753
- DOI
- 10.1101/638486