Article

ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing

2019-02-12

Abstract excerpt

<h4>ABSTRACT</h4> The zinc finger e-box binding homeobox 1 (ZEB1) transcription factor is a master regulator of the epithelial to mesenchymal transition (EMT), and of the reverse mesenchymal to epithelial transition (MET) processes. ZEB1 plays an integral role in mediating cell state transitions during cell lineage specification, wound healing and disease. EMT/MET are characterized by distinct changes in molecula...

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Literature Corpus work: 5a8aaf6e-4b2c-5bdb-b8ee-70d255c6c552
DOI: 10.1101/547927

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