Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy

Abstract excerpt

Homeostatic maintenance of corneal endothelial cells is essential for maintenance of corneal deturgescence and transparency. In Fuchs endothelial corneal dystrophy (FECD), an accelerated loss and dysfunction of endothelial cells leads to progressively severe visual impairment. An abnormal accumulation of extracellular matrix (ECM) is a distinctive hallmark of the disease, however the molecular pathogenic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Corneal surgery and disorders
• Share to Corneal Surgery and Treatments