Article

Priming is dispensable for NLRP3 inflammasome activation in human monocytes

2020-01-30

Abstract excerpt

<h4>ABSTRACT</h4> Interleukin (IL)-1 family of cytokines modulate immune responses during infection and inflammation. IL-18 and IL-1β are members of the IL-1 family, which contribute to inflammatory conditions such as rheumatoid arthritis and Alzheimer’s disease. IL-18 and IL-1β are produced as inactive precursors that are activated by large macromolecular complexes called inflammasomes upon sensing damage or pat...

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Literature Corpus work: 3219fcd3-a7fb-5a3e-bbad-b00387cbecdb
DOI: 10.1101/2020.01.30.925248

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