Back to search

Article

Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics data

2017-11-17

Abstract excerpt

<h4>Background</h4> The accuracy of microbial community surveys based on marker-gene and metagenomic sequencing (MGS) suffers from the presence of contaminants — DNA sequences not truly present in the sample. Contaminants come from various sources, including reagents. Appropriate laboratory practices can reduce contamination, but do not eliminate it. Here we introduce decontam ( https://github.com/benjjneb/deco...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
be09ba97-3c1c-5782-9462-e911b542240a
DOI
10.1101/221499
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Simple statistical identification and removal of contaminant sequences in marker-gene and metagenomics dataDOI 10.1101/221499
Select a neighboring publication to make it the new centre.