Article

Contaminant DNA in bacterial sequencing experiments is a major source of false genetic variability

2018-08-29

Abstract excerpt

Contaminant DNA is a well-known confounding factor in molecular biology and in genomic repositories. Strikingly, analysis workflows for whole-genome sequencing (WGS) data usually neglect the errors introduced by potential contaminations. We performed a comprehensive evaluation of the extent and impact of contaminant DNA in WGS by analyzing more than 4,000 bacterial samples from 20 different studies. We found that...

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Literature Corpus work: 638890b6-6f52-541b-84ff-2a0fa336d6a6
DOI: 10.1101/403824

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