Article

Self-Assembled Tetrahedral Framework Nucleic Acid Mediated Tumor-Associated Macrophages Reprogramming and Enhancing Cancer Immunotherapy

2021-04-01

Abstract excerpt

<title>Abstract</title> <p>There is increasing interest in depleting or repolarizing tumor-associated macrophages (TAMs) to generate a pro-inflammatory effect. However, TAMs usually display an immunosuppressive M2-like phenotype in tumor microenvironment. Apparently, developing a macrophage targeting delivery system with immunomodulatory agents is urgent. In the study, an efficient siRNAs and CpG ODNs delivery sy...

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Literature Corpus work: a7e7304a-4cdc-54a9-bae8-27a9dedc6246
DOI: 10.21203/rs.3.rs-373672/v1

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