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Bupivacaine inhibits a small conductance calcium-activated potassium type 2 channel (SK2) in HEK 293 cells

2019-02-20

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Bupivacaine blocks many ion channels in the heart muscle, which could cause severe cardiotoxicity. Small conductance calcium-activated potassium type 2 channels (SK2 channels) are widely distributed in the heart cells and are involved in relevant physiological functions. However, whether bupivacaine can inhibit SK2 channels is still unknown. This study investiga...

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Literature Corpus work
bddee37f-33dc-59c5-bed7-70511f53a1fd
DOI
10.21203/rs.2.338/v1
Open publication

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Bupivacaine inhibits a small conductance calcium-activated potassium type 2 channel (SK2) in HEK 293 cellsDOI 10.21203/rs.2.338/v1
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