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Article

Splicing of the rSlo gene affects the molecular composition and drug response of Ca2+-activated K+ channels in skeletal muscle.

PloS one - 1 Jan 2012

Dinardo Maria Maddalena, Camerino Giulia, Mele Antonietta, Latorre Ramon, Conte Camerino Diana, Tricarico Domenico

Abstract excerpt

The molecular composition and drug responses of calcium-activated K(+) (BK) channels of skeletal muscle are unknown. Patch-clamp experiments combined with transcript scanning of the Kcnma1 gene encoding the alpha subunit of the BK channel were performed in rat slow-twitch soleus (Sol) and fast-twitch flexor digitorum brevis (FDB) skeletal muscles. Five splicing products of the Kcnma1 gene were isolated from Sol...

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Identifiers

PMID: 22808126
DOI: 10.1371/journal.pone.0040235
PMCID: PMC3393747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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