Article

Tunneling nanotubes propagate preneoplastic cues in a BMP-dependent manner

2025-11-12

Abstract excerpt

Tunneling nanotubes (TNTs) are thin, actin-rich structures that facilitate long-distance intercellular communication through the transfer of molecules and organelles. While their role in cancer progression is well-established, their involvement in the earliest stages of tumor initiation remains unexplored. Using normal human mammary primary cells, a model of early luminal breast transformation, and mammary organoi...

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Identifiers and source

Literature Corpus work: 6f34005a-3902-58b1-bbbb-f76679231745
DOI: 10.1101/2025.11.11.687852

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